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Diabetes Spectrum 20:85-89, 2007
DOI: 10.2337/diaspect.20.2.85
© 2007 by the American Diabetes Association
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Polycystic Ovary Syndrome and Pregnancy: Is Metformin the Magic Bullet?

Howard Craig Zisser, MD

In Brief

This article reviews the literature regarding the effects of metformin therapy in pregnant women with polycystic ovary syndrome on weight loss, fertility, early pregnancy loss, malformations, gestational diabetes mellitus, perinatal mortality, placental clearance, lactation, and early childhood development. The pharmacology of metformin is also presented. Preliminary data suggest that metformin for this population may be both safe and effective. Large blinded, randomized clinical trials are underway to confirm the preliminary safety data.


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Related Article:

Lois Jovanovic
Diabetes Spectr 2007 20: 82-83. [Extract] [Full Text] [PDF]





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Copyright © 2007 by the American Diabetes Association.