HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text Full Text (PDF) Purchase Article View Shopping Cart Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Request Permissions Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Skala, J. A. Search for Related Content PubMed Articles by Skala, J. A. Social Bookmarking                What's this?

Hypothesis 5. Treatment of depression may reduce the risks of diabetes and its complications.

The first 20% of the full text of this article appears below.

	Foundation Article

 
Lustman PJ, Griffith LS, Freedland KE, Kissel SS, Clouse RE: Cognitive behavior therapy for depression in type 2 diabetes: a randomized, controlled trial. Ann Intern Med 129: 613–621, 1998

	Summary and Commentary

 
The preceding commentaries have reported evidence for the negative effects of depression on those with diabetes, e.g., poorer glycemic control and increased complications, as well as an elevated risk for development of diabetes in depressed subjects. Therefore, it is of great interest to know whether the risks conferred by depression can be modified if depression is successfully treated. Given the association between the above risks, lifestyle choices, and behaviors, it is likely that depression treatment that targets these factors may be particularly helpful, especially over the long term.

Cognitive behavior therapy (CBT) specifically addresses mistaken, maladaptive, or ruminative cognitions about one's self, one's relationships, and one's present and future circumstances. More accurate and helpful cognitive responses are formulated, and behavior is addressed in terms of adaptive problem-solving, improving relationships, and increasing enjoyable as well as productive activities.^46,47 CBT has been shown to improve depression in those with and without medical illness in numerous studies.^48–50

The first evidence that depression in patients with type 2 diabetes can be successfully treated by CBT was provided by this randomized, controlled trial reported by Lustman et al. For this study, 51 patients with type 2 diabetes and comorbid major depression were randomized to receive biweekly diabetes education either alone or in combination with 10 weekly CBT sessions for depression. Beck Depression Inventory score and glycated hemoglobin level were measured at the end of treatment and again 6 months after treatment. The dropout rate was low, and a completer analysis was used.

The percentage of . . . [Full Text of this Article]

CiteULike    Del.icio.us    Digg    Reddit    Technorati    What's this?