Diabetes Bars and Beverages: The Benefits and the Controversies

Functional Features of Diabetes Medical Foods

The complex formulation of the diabetes bars and beverages on the market responds to the mounting evidence that certain nutrients and physiologically active food components play a role in improving glycemic control and reducing risk factors for development of diabetes complications. Functional features in these products include resistant starch and added fiber; fortification with vitamins and minerals—specifically, notably high amounts of the antioxidant vitamins C and E and chromium; and the use of soy. Some products manipulate the percentages of the macronutrients carbohydrate, protein, and fat, while others incorporate herbal and other nontraditional remedies. (See Tables 1 and 2.)

In evaluating each product, it is important to determine whether there is sufficient evidence to support its purported role in diabetes management and whether the inclusion of a functional feature is truly efficacious.

Resistant starch and soluble fiber

Nutrition recommendations for people with diabetes advise that the total amount of carbohydrate consumed is more important than the source of carbohydrate. However, these same recommendations recognize that various starches cause different glycemic responses.3

Resistant starch is a carbohydrate source that requires special consideration. It withstands breakdown by digestive enzymes and thus is digested and absorbed at a slow and sustained rate. This results in a coinciding low postprandial blood glucose peak and a continued slow release of glucose into the bloodstream for several hours.4,5 Consequently, resistant starch, either in the form of uncooked cornstarch or produced through food processing, is a key functional feature of diabetes bars and beverages. Other benefits include a lowering of insulin response and improvement in insulin efficiency in the postprandial phase, an improvement in lipid metabolism as evidenced by lower LDL cholesterol and triglyceride levels, and improvements in fibrinolytic capacity.6–8 Because products that contain resistant starch, especially uncooked cornstarch, lead to a slow release of glucose into the blood-stream, they may help prevent hypoglycemia when incorporated into a nighttime snack or consumed as a pre-exercise carbohydrate source.9

Fiber fortification, especially with viscous water-soluble fiber, is another feature of diabetes bars and beverages. Water-soluble fiber delays transit time through the stomach and small intestine, and fiber viscosity slows the transit of chyme through the intestinal tract. This slows absorption rates and lowers blood concentrations of nutrients postprandially.10

High-fiber diets have been shown to lower postmeal blood glucose rise, improve insulin sensitivity, and reduce hyperinsulinemia,10–12 to reduce total cholesterol by ≥5%, to modestly reduce LDL cholesterol, and to lower triglyceride levels.11,12 Fiber may also favorably affect clotting factors.8

Although all individuals, including those with diabetes, are encouraged to consume 20–35 g/day of fiber from both soluble and insoluble sources,3 average daily fiber intake among Americans is only about 14–15 g.13 Individuals who have restricted calorie intakes may be especially vulnerable to an inadequate fiber intake. Although we must encourage consumption of a variety of fruits, vegetables, and whole grains, supplemental foods can be additional fiber sources.

Protein and fat

The mix of protein and fat in diabetes supplements serves the functional purpose of improving glycemic control and reducing cardiovascular risk factors (Tables 1 and 2). Most bars and beverages that are considered nutritionally complete are formulated to support the National Cholesterol Education Program14 guidelines for moderate fat, low saturated fat, and low cholesterol intake. These guidelines are especially important to help people with diabetes maintain desirable blood lipid levels.3,11

Fat is added to those diabetes bars that are formulated to prevent hypoglycemia because fat delays gastric emptying, slows the absorption of carbohydrate, and therefore delays the postprandial blood glucose peak. Because fat extends the nutrient absorption time and entrance into the bloodstream as glucose, its role in these products is to lower the risk of hypoglycemia.9

The ideal dietary protein mix is much debated, in part because of the influence of the once-again-popular low-carbohydrate, high-protein diet trend. Nutrition recommendations for people with diabetes advise that 10–20% of daily calories should come from protein.3 The percentage of protein in some bars designed for people with diabetes is as high as 30% of calories, whereas carbohydrate provides only 40% of calories in these products.

The high-protein formulation is based on the popular claims that protein has a low glycemic index, prevents high glucose excursions, decreases insulin levels, reduces fat storage, reduces hunger, and improves weight-loss success and glycemic control. These claims are very controversial and are of questionable accuracy.15 Soy protein, which is added to some products, is associated with a beneficial and significant lowering of total cholesterol, LDL cholesterol, and triglycerides without affecting HDL cholesterol.11,2

Protein serves another functional purpose in diabetes bars formulated to prevent hypoglycemia. It is added to these products based on the notion that it is converted to glucose and released into the bloodstream 2.5–5 h after it is consumed.9 Protein, therefore, contributes to a delayed postprandial blood glucose peak and may help prevent nighttime or exercise-related hypoglycemia.9 The degree to which protein is converted to glucose in the blood and the role that it plays in preventing hypoglycemia is another highly debated topic.15

Vitamins, minerals, and antioxidants

Historically, beverage supplements that are labeled “nutritionally complete” have been formulated to meet the nutritional needs of undernourished, hospitalized patients who depended on these products as a primary means of nourishment. Thus, they have been formulated to provide approximately 100% of the daily value (DV) for essential vitamins and minerals per 1,000 cc, the amount contained in about four, 8-oz. cans of beverage. These products, still touted as nutritionally complete, now target all individuals with diabetes. Many of the available bars and beverages provide 100% DV for vitamins C and E and chromium per serving. (See Tables 1 and 2.)

Considerable evidence suggests that oxidative processes are involved in the development of atherosclerotic diseases, and that antioxidants, especially vitamin E, play a role in lowering disease risk.11,16–18 Chromium supplementation is gaining popularity as its potential to improve insulin action, improve fasting and postprandial blood glucose, and reduce blood lipids gains acceptance.18,19 B vitamins, especially folic acid, are recognized to play a role in reducing homocysteine levels and may be beneficial in the prevention and treatment of vascular complications of diabetes,11,18 Because there is much research bringing good news about the benefits of these nutrients, they are popular additions to functional foods.

However, the potential for excess intake certainly exists. Diabetes bars and beverages can potentially contribute significant amounts of these nutrients to the total daily intake. Individuals with diabetes, either on their own or by advice of their physician, may also be supplementing these same vitamins and minerals in addition to consuming other highly fortified foods. Diabetes care providers must carefully assess total micronutrient intake from supplemental products in addition to the amounts taken in from all other sources to ensure that total intake is adequate but not above tolerable upper intake levels (UL).20

Interestingly, with the exception of folic acid, neither the American Diabetes Association, the American Dietetic Association, nor the American Heart Association support routine supplementation or fortification of these micronutrients. Rather, they encourage consuming a varied diet that includes plenty of plant foods.11,20

Implications for Use

Given the potential benefits and possible controversies surrounding diabetes medical foods, what advice should we offer individuals with diabetes about using these products?

• Diabetes snack bars and beverages are supplemental foods. They can be beneficial when appropriately incorporated into a diabetes meal plan but should not be routinely used as meal replacements.

• Some diabetes snack bars and beverages are formulated to blunt the postprandial blood glucose rise and thus reduce the incidence of hyperglycemia. These tend to be called “nutritionally complete” and can be either incorporated into a meal or snack as a carbohydrate choice or used as a calorie-controlled meal or snack replacement. In either case, their purpose is to cause a reduced postprandial glycemic effect. These products can be especially helpful to people with type 2 diabetes.

• Other snack bars, most containing uncooked cornstarch, are formulated to prevent hypoglycemia, especially at night. Their intended use is as part of a bedtime snack or as a pre- or postexercise snack. These products may be especially helpful to patients on intensive insulin therapy who are susceptible to hypoglycemia, particularly those with hypoglycemia unawareness.

• Diabetes snack bars and beverages are not appropriate treatments for hypoglycemia because they are formulated to cause a blunted or delayed rise in blood glucose. If an immediate-acting source of carbohydrate is needed, a conventional snack bar or other carbohydrate source that is quickly absorbed and causes a rapid blood glucose rise should be used.

• Snack bars that contain uncooked cornstarch may be useful in a number of diabetes management situations. They may help prevent hypoglycemia if consumed after alcohol ingestion. When incorporated into the breakfast meal, they may also help prevent morning postprandial blood glucose elevations associated with pregnancy.21

• Self-monitoring of blood glucose and careful record keeping will enable clinicians and people with diabetes to determine the effects of snack bars or beverages on blood glucose levels. Because each diabetes bar or beverage has a unique formulation, its glycemic effect may also be unique.

• The nutrient composition of all food products, including medical foods formulated for people with diabetes, should be evaluated with current nutrition guidelines and recommendations in mind.3,11 Ulti-mately, however, it is overall dietary practices and patterns of food intake over time rather than intake of a single food item that determines dietary health and success in achieving good glycemic control.