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From Research to Practice

Challenges and Strategies for Inpatient Diabetes Management in Older Adults

  1. Aidar R. Gosmanov1,2,
  2. Carlos E. Mendez3,4 and
  3. Guillermo E. Umpierrez5
  1. 1Department of Medicine, Division of Endocrinology, Albany Medical College, Albany, NY
  2. 2Section of Endocrinology, Stratton VA Medical Center, Albany, NY
  3. 3Department of Medicine, Medical College of Wisconsin, Milwaukee, WI
  4. 4Division of Diabetes and Endocrinology, Milwaukee VA Medical Center, Milwaukee, WI
  5. 5Department of Medicine, Division of Endocrinology, Metabolism, and Lipids, Emory University School of Medicine, Atlanta, GA
  1. Corresponding author: Aidar R. Gosmanov, aidar.gosmanov{at}va.gov
Diabetes Spectrum 2020 Aug; 33(3): 227-235. https://doi.org/10.2337/ds20-0008
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    FIGURE 1

    Management approach for inpatient hyperglycemia in elderly patients with type 2 diabetes in the non-ICU setting. *Basal insulin glargine, detemir, or degludec once daily starting at 0.1 unit/kg/day and adjusting as needed to achieve target blood glucose. **Reduce home insulin dose by 25% on admission if patient is eating or by 50% if patient has poor oral intake. Basil, basil insulin; BG, blood glucose; d, day; DPP4i, DPP-4 inhibitor; prandial, prandial insulin; U, units.

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  • TABLE 1

    Most Recent Professional Societies’ Recommendations on Inpatient Glycemic Targets for Older Patients

    Society, Year (reference)Critically Ill, mg/dLNoncritically Ill, mg/dLNotes Regarding Older Patients
    FastingPostprandial
    ADA/AACE, 2009 (18)110–180100–140100–180No specific recommendations for older patients
    International Diabetes Federation, 2014 (22)—<140<180These targets are for older patients.
    Diabetes Canada, 2018 (21)110–18090–140<180No specific recommendations for older patients
    Endocrine Society, 2019 (23)—100–140140–180These targets are for older patients.
    Joint British Diabetes Societies for Inpatient Care, 2019 (24)140–180140–180100–216 mg/dL (6–12 mmol/L) is acceptable for older patients.
    American Diabetes Association, 2020 (19)140–180140–180No specific recommendations for older patients; >180 mg/dL (10.0 mmol/L) in patients with severe comorbidities
  • TABLE 2

    Framework for an Individualized Approach to the Pre-Discharge Evaluation of Older, Hospitalized Patients With Diabetes

    1. Evaluate for geriatric syndrome:
     • Depression
     • Urinary incontinence
     • Fall risk
     • Vision/hearing problems
    2. Avoid polypharmacy.
    3. Set outpatient A1C target.
    4. Avoid complexity of antihyperglycemic regimen.
    5. Reassess regarding whether metformin can be continued or initiated.
    6. Reduce the risk of hypoglycemia:
     • Limit use of sulfonylurea medications.
     • Use physiologic insulin regimens.
     • Prefer use of only basal insulin in the early phases of hyperglycemia correction.
     • Consider a DPP-4 inhibitor instead of initiation or escalation of insulin in patients with an A1C <9.0%.
    7. Provide close follow-up in outpatient setting.
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Diabetes Spectrum: 33 (3)

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Challenges and Strategies for Inpatient Diabetes Management in Older Adults
Aidar R. Gosmanov, Carlos E. Mendez, Guillermo E. Umpierrez
Diabetes Spectrum Aug 2020, 33 (3) 227-235; DOI: 10.2337/ds20-0008

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Challenges and Strategies for Inpatient Diabetes Management in Older Adults
Aidar R. Gosmanov, Carlos E. Mendez, Guillermo E. Umpierrez
Diabetes Spectrum Aug 2020, 33 (3) 227-235; DOI: 10.2337/ds20-0008
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  • Management of Diabetes Across the Life Spectrum
  • About Medha N. Munshi, MD: Guest Editor, Management of Diabetes Across the Life Spectrum
  • Challenges and Strategies for Managing Diabetes in the Elderly in Long-Term Care Settings
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