TABLE 1.

Insulin Formulations

Insulin FormulationTypical Dosing
Basal insulin
Intermediate-acting NPH insulinTwice daily
Long-acting insulins
 Detemir
 Glargine
 Glargine U-300
 Degludec
 Degludec U-200
Once or twice daily
Once daily
Once daily
Once daily
Once daily
Bolus insulin
Rapid-acting insulins
 Aspart
 Glulisine
 Lispro
 Inhaled insulin
Three times daily before meals
Three times daily before meals
Three times daily before meals
Three times daily before meals
Short-acting insulins
 Regular human insulin
 Regular human insulin U-500
Three times daily before meals
Two to three times daily without basal insulin
Premixed insulin
NPH/regular
 70/30
 50/50
Twice daily
Twice daily
Aspart protamine/aspart
 30/70
 50/50
 70/30
Twice daily
Twice daily
Twice daily
Lispro protamine/lispro
 50/50
 75/25
Twice daily
Twice daily
Degludec/aspart 70/30Twice daily