Characteristics of Type 1 Diabetes, Type 2 Diabetes, and LADA
| Type 1 Diabetes | Type 2 Diabetes | LADA | |
|---|---|---|---|
| Age (years) | <35 | >35 | ≥30 |
| C-peptide | Very low | Normal to high | Low |
| ICA | Often positive | Negative | Can be positive |
| GAD65 | Often positive | Negative | Can be positive |
| IA-2 | Often positive | Negative | Can be positive |
| IAA | Often positive | Negative | Can be positive |
| Circulating insulin | Rapidly deficient | Excessive and resistant | Gradually deficient |
| Time to requiring insulin | At onset | Can be many years | Within 6 months (variable) |