TABLE 1.

Summary of Blood Pressure Goals and Initial Choice of Antihypertensive Agent for Patients With Diabetes Endorsed by Different Professional Societies or Expert Groups

Recommendation (Year)Blood Pressure Goals (mmHg)First-Line Pharmacological Treatment
ADA (2018)<140/90 (<130/80*)ACEI/ARB, thiazide-like diuretic, or dihydropyridine CCB
ACC/AHA (2017)<130/80No preference
JNC 8 (2014)<140/90Non-black: ACEI/ARB, thiazide-like diuretic, or CCB Black: thiazide-like diuretic or CCB
VA/DoD (2014)<150/85 (140/85**)Thiazide-like diuretic (chlorthalidone or indapamide)
CDA (2013)<130/80ACEI/ARB, thiazide-like diuretic, or dihydropyridine CCB
ESH/ESC (2013)<140/85ACEI/ARB, thiazide-like diuretic, or CCB
  • * May be appropriate for individuals at high risk of CVD.

  • ** Suggested for patients who can tolerate the antihypertensive medications necessary to reach this goal.

  • Recommended if hypertension is associated with proteinuria and suggested if hypertension is associated with microalbuminuria as the preferred first-line agent.

  • Recommended in the presence of known kidney disease, including microalbuminuria, or CVD.