TABLE 1

Studies Showing the Effects of IF on A1C and Weight Loss in Adults With Type 2 Diabetes

Groups..Design..n..Mean Age, yearsStudy Duration, months.Primary Outcome..Mean Weight Change From Baseline, kgMean A1C Change From Baseline, %P for Change in A1C
Sundfør et al. (12)IntermittentRCT5449.912Weight loss−9.1−0.30.2
Continuous5847.5−9.4−0.20.2
Carter et al. (13)IntermittentRCT7061.012A1C−6.8−0.3<0.001
Continuous6761.0−5.0−0.5<0.001
Corley et al. (14)ConsecutiveRCT1962.03Hypoglycemia−3.6−0.60.53
Nonconsecutive2258.03−3.1−0.70.53
Li et al. (15)FastingRCT2364.74Weight loss−3.5−0.20.30
Control2365.4−2.0−0.20.28
Williams et al. (17)1-day VLCDRCT1851.44Weight loss and glycemic control−16.5−0.710.38
5-day VLCD1850.34−10.4−0.970.38
Control1854.14−5.4−0.230.38